The main ingredient in revolution is selamectin.
Revolution selamectin for dogs side effects.
There have been reports of a few collies drooling and staggering when overdosed with.
Selamectin solution also was administered at 3 times the recommended dose to heartworm infected dogs and no adverse effects were observed.
Revolution is also safe for use in dogs over 6 weeks of age and cats over 8 weeks.
Selamectin is the active ingredient and is a neurotoxin which attacks the central nervous system it is not meant to cross the brain blood barrier in mammals but does in fleas etc.
Like other drugs it does carry the risk of certain side effects.
Side effects and risks of selamectin.
Selamectin is a synthetic ingredient that gets into the parasite s system and replaces an important amino acid that controls the release of chloride into the bloodstream.
Selamectin is generally considered safe for use in animals of all ages and types.
However it should be avoided if at all possible in animals that are younger than 6 weeks of age or that are underweight.
Although it is applied to the skin revolution has a holistic effect that targets both internal and external parasites.
As a result the chloride enters the parasite s nerve cells causing paralysis and death.
No adverse reactions were observed.
Selamectin is however safe to use in pregnant or lactating pets.
Vomiting loose stools diarrhea with or without blood anorexia lethargy salivation tachypnea and muscle tremors are other revolution side effects in dogs listed but they are claimed by pfizer s insert to be rare 0 5 of 1743 cats and dogs treated.
The administration of selamectin may result in oily stiff discolored or powdery hair or skin at the administration site.
Reading the studies on revolution side effects it does talk about some animals having adverse effects.
In safety studies selamectin solution was applied at 1 3 5 and 10 times the recommended dose to six week old kittens.
Ingredients in revolution for dogs.
Sarolaner one of the ingredients in revolution plus is a member of the isoxazoline class which has been associated with adverse reactions such as tremors ataxia and seizures.
It is safe and simple to apply topically on dogs and cats.
Selamectin is a topical agent and temporary irritation and hair loss at the site of application is possible.
Side effects are rare and may include vomiting diarrhea anorexia drooling lethargy or muscle tremors associated with ingestion of selamectin.
